Grant Publications

Proposal No.  IBD-0001
Principal Investigator:  Giamila Fantuzzi, Ph.D.
Applicant Organization:  University of Colorado (Denver, U.S.A.)
Project Title:  The leptin receptor:  Role in inflammatory bowel disease 
Period of Award:  January 1, 2002 - February 29, 2004

Siegmund B, Lehr HA, Fantuzzi G.  Leptin:  a pivotal mediator of intestinal inflammation in mice.  Gastroenterology 2002;122:2011-25.

Siegmund B, Sennello JA, Jones-Carson J, Gamboni-Robertson F, Lehr HA, Batra A, Fedke I, Zeitz M, Fantuzzi G.  Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice.  Gut 2004;53:965-72.

Siegmund B, Sennello JA, Lehr HA, Batra A, Fedke I, Zeitz M, Fantuzzi G.  Development of intestinal inflammation in double IL-10- and leptin-deficient mice.  Journal of Leukocyte Biology 2004;76:782-6.

Siegmund B, Sennello JA, Lehr HA, Senaldi G, Dinarello CA, Fantuzzi G.  Interferon regulatory factor-1 as a protective gene in intestinal inflammation:  role of TCR gamma-delta T cells and interleukin-18-binding protein.  European Journal of Immunology 2004;34:2356-64.