Grant Publications

Proposal No.   IBD-0037
Principal Investigator:  Daniel Rachmilewitz, M.D.
Applicant Organization:  Shaare Zedek Medical Center (Jerusalem, Israel)
Project Title: Immunostimulatory DNA for the treatment of inflammatory bowel disease
Period of Award:  December 1, 2002 – November 30, 2004

Rachmilewitz D, Katakura K, Karmeli F, Hayashi T, Reinus C, Rudensky B, Akira S, Takeda K, Lee J, Takabayashi K, Raz E.  Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis.  Gastroenterology 2004;126:520-8.

Lee J, Rachmilewitz D, Raz E.  Homeostatic effects of TLR9 signaling in experimental colitis.  Annals of the New York Academy of Sciences 2006;1072:351-5.

Rachmilewitz D, Karmeli F, Shteingart S, Lee J, Takabayashi K, Raz E. Immunostimulatory oligonucleotides inhibit colonic proinflammatory cytokine production in ulcerative colitis.   Inflammatory Bowel Diseases 2006;12(5):339-45.