Grant Publications

Proposal No.   IBD-0092R
Principal Investigator:  Konstantinos Papadakis, M.D.
Applicant Organization:   Cedars-Sinai Medical Center (Los Angeles, California, U.S.A.)
Project Title:  Phenotypic and functional characterization of CCR9+ T lymphocytes in small intestinal Crohn’s disease
Period of Award:  April 1, 2004 – December 31, 2005

Papadakis KA, Zhu D, Prehn JL, Landers C, Avanesyan A, Lafkas G, Targan SR.  Dominant role for TL1A/DR3 pathway in IL-12 plus IL-18-induced IFN-gamma production by peripheral blood and mucosal CCR9+ T lymphocytes.  tThe Journal of Immunology 2005;174:4985-90.

Yu QT, Saruta M, Avanesyan A, Fleshner PR, Banham AH, Papadakis KA.  Expression and functional characterization of FOXP3+CD4+ regulatory T cells in ulcerative colitis.  Inflammatory Bowel Diseases 2007:13:191-9.

Saruta M, Yu QT, Avanesyan A, Fleshner PR, Targan SR, Papadakis KA.  Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease.  The Journal of Immunology 2007;178:3293-300.

Saruta M, Yu QT, Fleshner PR, Mantel PY, Schmidt-Weber CB, Banham AH, Papadakis KA.  Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease.  Clinical Immunology 2007;125:281-90.