Grant Publications

Proposal No.  IBD-0093R2
Principal Investigator:  Jonathan Braun, M.D., Ph.D.
Applicant Organization:  University of California, Los Angeles (U.S.A.)
Project Title:  The intestinal fungi:  role in microbial consortia and mucosal immune homeostasis
Period of Award:  October 1, 2004 - March 31, 2006

Huang T, Wei B, Velazquez P, Borneman J, Braun J.  Commensal microbiota alter the abundance and TCR responsiveness of splenic naïve CD4+ T lymphocytes.  Clinical Immunology 2005;117:221-30.

Scupham AJ, Presley LL, Wei B, Bent E, Griffith N, McPherson, M, Zhu F, Oluwadara O, Tao Nagesh, Braun J, Borneman J.  Abundant and diverse fungal microbiota in the murine intestine.  Applied and Environmental Microbiology 2005;72:793-801.

An G, Wei B, Xia B, McDaniel JM, Ju T, Cummings RD, Braun J, Xia L.  Increase susceptibility to colitis and colorectal tumors in mice lacking core 3-derived o-glycans.  Journal of Experimental Medicine 2007;204:1417-29.

Braun J, Wei B.  Body traffic:  ecology, genetics, and immunity in inflammatory bowel disease.  Annual Review of Pathology:  Mechanisms of Disease 2007;2:401-29.

Fujiwara D, Wei B, Presley LL, Brewer S, McPherson M, Lewinski MA, Borneman J, Braun J.  Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota.  Journal of Immunology 2008;180:5843-52.

Underhill D, Braun J.  Current understanding of fungal microflora in inflammatory bowel disease pathogenesis.  Inflammatory Bowel Diseases 2008;14:1147-53.

Velázquez P, Wei B, McPherson M, Mendoza LM, Nguyen SL, Turovskaya O, Kronenberg M, Huang TT, Schrage M, Lobato LN, Fujiwara D, Brewer S, Arditi M, Cheng G, Sartor RB, Newberry RD, Braun J.  Villous B cells of the small intestine are specialized for invariant NK T cell dependence.  Journal of Immunology 2008;180:4629-38.

Ye J, Lee JW, Presley LL, Bent E, Wei B, Braun J, Schiller NL, Straus DS, Borneman J.  Bacteria and bacterial rRNA genes associated with the development of colitis in IL-10(-/-) mice.  Inflammatory Bowel Diseases 2008;14:1041-50.

Presley LL, Wei B, Braun J, Borneman J.  Bacteria associated with immunoregulatory cells in mice.  Applied and Environmental Microbiology 2010;76:936-41.

Wei B, Wingender G, Fujiwara D, Chen DY, McPherson M, Brewer S, Borneman J, Kronenberg M, Braun J.  Commensal microbiota and CD8+ T cells shape the formation of invariant NKT cells.  Journal of Immunology 2010;184:1218-26.