Grant Publications

Proposal No.    IBD-0116R
Principal Investigator:  Christian Jobin, Ph.D.
Applicant Organization:  University of North Carolina at Chapel Hill (U.S.A.)
Project Title:  Modulation of innate signal transduction and experimental colitis by natural plant extracts
Period of Award:  July 1, 2004 - December 31, 2005

Kim JS, Jarula AS, Jobin C.  Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-κB signalling in intestinal epithelial cells.  Clinical and Experimental Immunology 2005;141:288-97.

Kim JS, Jobin C.  The flavonoid luteolin prevents lipopolysaccharide-induced NF-κB signalling and gene expression by blocking IκB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells.  Immunology 2005;115:375-87.