Grant Publications

Proposal No.  IBD-0126R2
Principal Investigator:  Helga-Paula Török, M.D. (replacement PI); Christian Folwaczny, M.D. (original PI)
Applicant Organization:  Klinikum der Universität München (Germany)
Project Title:  NOD2/CARD15 mutations and apoptosis in Crohn's disease
Period of Award:  July 1, 2005 – March 31, 2007

Török HP, Glas J, Lohse P, Folwaczny C.  Genetic variants and the risk of Crohn's disease:  what does it mean for future disease management?  Expert Opinion on Pharmacotherapy 2006;7:1591-602.

Glas J, Seiderer J, Wetzke M, Konrad A, Török HP, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Maier K, Griga T, Klein W, Epplen JT, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Brand S.  rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.  PLoS ONE 2007;2:e819.

Beynon V, Cotofana S, Brand S, Lohse P, Mair A, Wagner S, Mussack T, Ochsenkühn T, Folwaczny M, Folwaczny C, Glas J, Török HP. NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes. Inflammatory Bowel Diseases 2008;14:1033-40.