Grant Publications

Proposal No.  IBD-0148R
Principal Investigator:  Michael Zasloff, M.D., Ph.D.
Applicant Organization:  Georgetown University (Washington, District of Columbia, U.S.A.)
Project Title:  Antimicrobial peptide expression and its relationship to commensal bacteria in the transplanted small bowel
Period of Award:  July 25, 2005 – July 31, 2008

Fishbein T, Novitskiy G, Mishra L, Matsumoto C, Kaufman S, Goyal S, Shetty K, Johnson L, Lu A, Wang A, Hu F, Kallakury B, Lough D, Zasloff M. NOD2-expressing bone marrow-derived cells appear to regulate epithelial innate immunity of the transplanted human small intestine.  Gut 2008;57:323-30.

Fishbein TM, Novitskiy G, Lough DM, Matsumoto C, Kaufman SS, Shetty K, Zasloff M.  Rejection reversibly alters enteroendocrine cell renewal in the transplanted small intestine.  American Journal of Transplantation 2009;9:1620-8.

Hartman AL, Lough DM, Barupal DK, Fiehn O, Fishbein T, Zasloff M, Eisen JA.  Human gut microbiome adopts an alternative state following small bowel transplantation.  Proceedings of the National Academy of Sciences 2009;106:17187-92.