Grant Publications

Proposal No. IBD-0193R
Principal Investigator: Anthony W. Segal, M.D., Ph.D., D.Sc.
Applicant Organization: University College London (United Kingdom)
Project Title: Impaired innate immunity and the pathogenesis of Crohn’s disease
Period of Award: March 1, 2007 – February 29, 2008

Rahman FZ, Hayee B, Chee R, Segal AW, Smith AM.  Impaired macrophage function following bacterial stimulation in chronic granulomatous disease.  Immunology 2009;128:253-9.

Smith AM, Rahman RZ, Hayee B, Graham SJ, Marks D, Sewell GW, Palmer CD, Wilde J, Foxwell B.  Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.  Journal of Experimental Medicine 2009;206:1883-97.