Grant Publications

Proposal No.   IBD-0211
Principal Investigator: Lee A. Denson, M.D.
Applicant Organization:  Cincinnati Children's Hospital Medical Center (Ohio, U.S.A.)
Project Title: GM-CSF bioactivity and IBD phenotype
Period of Award:  October 1, 2007 - September 30, 2009

Han X, Uchida K, Jurickova I, Koch D, Willson T, Samson C, Bonkowski E, Trauernicht A, Kim MO, Tomer G, Dubinsky M, Plevy S, Kugathsan S, Trapnell BC, Denson LA.  Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease.  Gastroenterology 2009;136:1261-71.

Uchida K, Nakata K, Suzuki T, Luisetti M, Watanabe M, Koch DE, Stevens CA, Beck DC, Denson LA, Carey BC, Keicho N, Krischer JP, Yamada Y, Trapnell BC.  Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects.  Blood 2009;113:2547-56.

Nylund CM, D'Mello S, Kim MO, Bonkowski E, Däbritz J, Foell D, Meddings J, Trapnell BC, Denson LA.  Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease.  Journal of Pediatric Gastroenterology and Nutrition 2011;52:542-8.

Samson CM, Jurickova I, Molden E, Schreiner W, Colliver J, Bonkowski E, Han X, Trapnell BC, Denson LA.  Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice.  Inflammatory Bowel Diseases 2011;17:2443-55.