Grant Publications

Proposal No. IBD-0218
Principal Investigator:  Bo Shen, M.D., M.S.
Applicant Organization:  The Cleveland Clinic Foundation (Ohio, U.S.A.)
Project Title:  Pouchitis: a human model for bacteria-host interaction in inflammatory bowel disease
Period of Award:  November 1, 2007 – April 30, 2010

Yu E, Shao Z, Shen B. Pouchitis. World Journal of Gastroenterology 2007;13:5598-604.

Shen B, Plesec T, Remzi FH, Kariv R, Lopez R, Queener E, Fazio VW, Goldblum JR.  Evaluation of tissue eosinophilia in the pouch and afferent limb in patients with restorative proctocolectomy.  Inflammatory Bowel Diseases 2008;14:744-9.

Shen B, Remzi FH, Brzezinski A, Lopez R, Bennett AE, Lavery IC, Queener E, Fazio VW.  Risk factors for pouch failure in patients with different phenotypes of Crohn's disease of the pouch.  Inflammatory Bowel Diseases 2008;14:942-8.

Navaneethan U, Remzi FH, Nutter B, Fazio VW, Shen B.  Risk factors for abnormal liver function tests in patients with ileal pouch-anal anastomosis for underlying inflammatory bowel disease.  American Journal of Gastroenterology 2009;104:2467-75.

Navaneethan U, Shen B.  Laboratory tests for patients with ileal pouch-anal anastomosis: clinical utility in predicting, diagnosing, and monitoring pouch disorders.  American Journal of Gastroenterology 2009;104:2606-15. 

Shen B, Remzi FH, Hammel JP, Lashner BA, Bevins CL, Lavery IC, Wehkamp J, Fazio VW.  Family history of Crohn's disease is associated with an increased risk for Crohn's disease of the pouch.  Inflammatory Bowel Diseases 2009;15:163-70.

Shen B, Remzi FH, Nutter B, Bennett AE, Lashner BA, Lavery IC, Brzezinski A, Bambrick ML, Queener E, Fazio VW.  Association between immune-associated disorders and adverse outcomes of ileal pouch-anal anastomosis.  American Journal of Gastroenterology 2009;104:655-64.

Kariv R, Plesec TP, Gaffney K, Lian L, Fazio VW, Remzi FH, Lopez R, Goldblum JR, Shen B.  Pyloric gland metaplasia and pouchitis in patients with ileal pouch-anal anastomoses.  Alimentary Pharmacology & Therapeutics 2010;31:862-73.

Kariv R, Remzi FH, Lian L, Bennett AE, Kiran RP, Kariv Y, Fazio VW, Lavery IC, Shen B.  Preoperative colorectal neoplasia increases risk for pouch neoplasia in patients with restorative proctocolectomy.  Gastroenterology 2010;139:806-12.

Lu H, Lian L, Navaneethan U, Shen B.  Clinical utility of C-reactive protein in patients with ileal pouch anal anastomosis.  Inflammatory Bowel Diseases 2010;16:1678-84. 

Navaneethan U, Shen B.  Secondary pouchitis: those with identifiable etiopathogenetic or triggering factors.  American Journal of Gastroenterology 2010;105:51-64.

Shen B, Patel S, Lian L.  Natural history of Crohn's disease in patients who underwent intentional restorative proctocolectomy with ileal pouch-anal anastomosis.  Alimentary Pharmacology & Therapeutics 2010;31:745-753.