Grants Funded in 2008
Principal Investigator: Boone, David, M.D.
Proposal No. IBD-0259
Applicant Organization: The University of Chicago (U.S.A.)
Project Title: Functional consequences of autophagy mutations in Crohn's disease
Period of Award: December 1, 2008 – February 28, 2010
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Principal Investigator: Brown, Amy, Ph.D., R.D.
Proposal No. IBD-0258R
Applicant Organization: University of
Project Title: The relationship of a “Crohn’s disease diet” in reducing symptoms of Crohn’s disease, improving quality of life, and decreasing related health care costs
Period of Award: December 1, 2008 – November 30, 2011
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Principal Investigator: Chamaillard, Mathias, Ph.D.
Proposal No. IBD-0222R
Applicant Organization: Institut Pasteur de Lille (France)
Project Title: Role of a c-type lectin on NOD2 signaling in Crohn's disease
Period of Award: April 1, 2008 – February 28, 2011
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Principal Investigator: Cherayil, Bobby J., M.D.
Proposal No. IBD-0253
Applicant Organization: Massachusetts General Hospital (U.S.A.)
Project Title: Iron-based modulation of cytokine biosynthesis for treatment of intestinal inflammation
Period of Award: November 1, 2008 – February 28, 2011
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Principal Investigator: Collins, Michael T., D.V.M., Ph.D.
Proposal No. IBD-0233
Applicant Organization: University of Wisconsin, Madison (U.S.A.)
Project Title: Evidence-based selection of antibiotics for treatment of Crohn's disease
Period of Award: January 1, 2008 – February 28, 2009
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Principal Investigator: Creagh, Emma M., Ph.D.
Proposal No. IBD-0197
Applicant Organization: University of Dublin, Trinity College (Ireland)
Project Title: Understanding the role and regulation of caspase-1 activation in inflammatory bowel disease
Period of Award: May 1, 2008 – April 30, 2012
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Principal Investigator: Danese, Silvio, M.D., Ph.D.
Proposal No. IBD-0224R2
Applicant Organization: Fondazione Humanitas per la Ricerca (Italy)
Project Title: The role of lymphangiogenesis in inflammatory bowel disease pathogenesis
Period of Award: April 1, 2008 – September 30, 2010
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Principal Investigator: Desseyn, Jean-Luc, Ph.D.
Proposal No. IBD-0220
Applicant Organization: INSERM (Institut National de la Santé et de la Recherche Médicale) (France)
Project Title: Protective action of a cysteine-rice mucin domain on the intestinal mucosa in experimental colitis
Period of Award: February 1, 2008 – March 31, 2010
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Principal Investigator: Dieleman, Levinus, M.D., Ph.D.
Proposal No. IBD-0243
Applicant Organization: University of Alberta (Canada)
Project Title: Capsule endoscopy for the assessment of abnormal intestinal permeability in Crohn’s disease relatives
Period of Award: November 1, 2008 – February 28, 2012
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Principal Investigator: Ganley-Leal, Lisa, Ph.D.
Proposal No. IBD-0235
Applicant Organization: Boston Medical Center (U.S.A.)
Project Title: Human B cells as potential mediators of inflammation in chronic inflammatory disease
Period of Award: November 1, 2008 – June 30, 2011
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Principal Investigator: Gearry, Richard B., M.B.Ch.B., Ph.D.
Proposal No. IBD-0236
Applicant Organization: University of Otago (New Zealand)
Project Title: A novel cellular assay system to assess the potential role of Mycobacterium avium subsp. paratuberculosis in the development and progression of Crohn's disease
Period of Award: June 1, 2008 – March 31, 2010
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Principal Investigator: Houghton, JeanMarie, M.D., Ph.D.
Proposal No. IBD-0230R2
Applicant Organization: University of Massachusetts Medical School (U.S.A.)
Project Title: Investigation of bone marrow derived stem cell recruitment to the colon in inflammatory bowel disease; direct and indirect role in carcinogenesis
Period of Award: July 1, 2008 - December 31, 2010
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Principal Investigator: Kellermayer, Richard, M.D., Ph.D.
Proposal No. IBD-0252
Applicant Organization: Baylor College of Medicine (U.S.A.)
Project Title: Identification of epigenetic correlates in inflammatory bowel diseases from human peripheral blood leukocyte DNA
Period of Award: November 1, 2008 – April 30, 2012
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Principal Investigator: Kuo, Calvin, M.D., Ph.D.
Proposal No. IBD-0237R
Applicant Organization: Stanford University (U.S.A.)
Project Title: Intestinal stem cells for therapy of inflammatory bowel diseases
Period of Award: September 1, 2008 - August 31, 2010
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Principal Investigator: Lundberg, Jon, M.D., Ph.D.
Proposal No. IBD-0206
Applicant Organization: Karolinska Institutet (Sweden)
Project Title: Nitrated fatty acids and inflammatory bowel disease
Period of Award: March 1, 2008 – February 28, 2009
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Principal Investigator: Mackner, Laura, Ph.D.
Proposal No. IBD-0231R
Applicant Organization: The Research Institute at Nationwide Children's Hospital (U.S.A.)
Project Title: Depression, cytokines, and cortisol in pediatric inflammatory bowel disease
Period of Award: June 1, 2008 – May 31, 2010
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Principal Investigator: Monteleone, Giovanni, M.D., Ph.D.
Proposal No. IBD-0242
Applicant Organization: University of Rome "Tor Vergata" (Italy)
Project Title: Antagonistic effects of interleukin-25 on CD14+ cell cytokine responses in the gut
Period of Award: June 1, 2008 – June 30, 2010
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Principal Investigator: Mullin, James M., Ph.D.
Proposal No. IBD-0227R
Applicant Organization: Lankenau Institute for Medical Research (U.S.A.)
Project Title: Improvement in gastrointestinal barrier function and morbidity by restriction of sulfur-containing amino acids in Crohn's disease patients
Period of Award: October 1, 2008 - June 30, 2010
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Principal Investigator: Naser, Saleh A., Ph.D.
Proposal No. IBD-0207R
Applicant Organization: University of Central Florida (U.S.A.)
Project Title: Role of Mycobacterium paratuberculosis (MAP) in family members with Crohn’s disease: genetic link and environmental influence
Period of Award: January 1, 2008 – February 28, 2011
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Principal Investigator: O'Mahony, Liam, Ph.D.
Proposal No. IBD-0221R
Applicant Organization: University College Cork (Ireland)
Project Title: Building a computation modeling foundation for emerging information for inflammatory bowel disease
Period of Award: January 7, 2008 – March 6, 2009
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Principal Investigator: Sørensen, Henrik Toft, Ph.D., Dr.Med.Sc.
Proposal No. IBD-0217
Applicant Organization: Aarhus University (Denmark)
Project Title: The association between inflammatory bowel disease and completed suicide in the adult population of Denmark
Period of Award: January 1, 2008 – February 28, 2009
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Principal Investigator: Stappenbeck, Thaddeus, S., M.D., Ph.D.
Proposal No. IBD-0250
Applicant Organization: Washington University (U.S.A.)
Project Title: Identification of colitogenic bacteria in an antibiotic-responsive model of fulminant ulcerative colitis
Period of Award: September 1, 2008 - February 28, 2011
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Principal Investigator: Terry, Paul D., Ph.D., MPH (replacement PI); Mandel, Jack S., Ph.D., MPH (original PI)
Proposal No. IBD-0223R
Applicant Organization: Emory University (U.S.A.)
Project Title: Melatonin supplementation and ulcerative colitis: a pilot randomized clinical trial
Period of Award: May 1, 2008 – April 30, 2009
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Principal Investigator: Toback, F. Gary, M.D., Ph.D.
Proposal No. IBD-0229
Applicant Organization: The University of Chicago (U.S.A.)
Project Title: Assessment of therapeutic efficacy of a novel peptide in murine models of human IBD
Period of Award: April 1, 2008 – February 28, 2011
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Principal Investigator: van der Woude, Christien Janneke, M.D., Ph.D.
Proposal No. IBD-0232
Applicant Organization: Erasmus University Medical Center (The Netherlands)
Project Title: The cost-effectiveness of fatigue management in patients with Crohn’s disease
Period of Award: November 1, 2008 – August 31, 2010
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Principal Investigator: van Die, Irma, Ph.D.
Proposal No. IBD-0234R
Applicant Organization: VU University Medical Center (The Netherlands)
Project Title: Protection against inflammatory bowel disease by glycan antigens
Period of Award: November 1, 2008 - July 31, 2011
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Principal Investigator: Virgin, Herbert W., M.D., Ph.D.
Proposal No. IBD-0246
Applicant Organization: Washington University (U.S.A.)
Project Title: In vivo function of Crohn’s disease susceptibility gene ATG16L1 in intestinal inflammation
Period of Award: September 1, 2008 - February 28, 2011
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