Grant Publications

Proposal No. IBD-0252
Principal Investigator: Richard Kellermayer, M.D., Ph.D.
Applicant Organization: Baylor College of Medicine (Houston, Texas, U.S.A.)
Project Title: Identification of epigenetic correlates in inflammatory bowel diseases from human peripheral blood leukocyte DNA
Period of Award: November 1, 2008 – October 31, 2011

Balasa A, Gathungu G, Kisfali P, Smith EO, Cho JH, Melegh B, Kellermayer R.  Assessment of DNA methylation at the interferon regulatory factor 5 (IRF5) promoter region in inflammatory bowel diseases.  International Journal of Colorectal Disease 2010;25:553-6.

Kellermayer R, Balasa A, Zhang W, Lee S, Mirza S, Chakravarty A, Szigeti R, Laritsky E, Tatevian N, Smith CW, Shen L, Waterland RA.  Epigenetic maturation in colonic mucosa continues beyond infancy in mice.  Human Molecular Genetics 2010;19:2168-76.

Sivagnanam M, Schaible T, Szigeti R, Byrd RH, Finegold MJ, Ranganathan S, Gopalakrishna GS, Tatevian N, Kellermayer R.  Further evidence of EpCAM as the gene for congenital tufting enteropathy.  American Journal of Medical Genetics 2010;152A:222-4.

Kellermayer R, Dowd SE, Harris RA, Balasa A, Schaible TD, Wolcott RD, Tatevian N, Szigeti R, Li Z, Versalovic J, Smith CW.  Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice.  The FASEB Journal 2011;25:1449-60.

Nagy-Szakal D, Kellermayer R.  The remarkable capacity for gut microbial and host interactions.  Gut Microbes 2011;2:178-82.

Schaible TD, Harris RA, Dowd SE, Smith CW, Kellermayer R.  Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes.  Human Molecular Genetics 2011;20:1687-96.