Grant Publications

Proposal No. IBD-0240R2
Principal Investigator: Paris Tekkis, M.D. 
Applicant Organization: Imperial College of Science, Technology and Medicine (London, England)
Project Title: Investigation of the bacterial pathogenesis of inflammation of the ileal reservoir following restorative proctocolectomy for ulcerative colitis and familial adenomatous polyposis 
Award Period: April 1, 2009 – September 30, 2010

McLaughlin SD, Clark SK, Roberts CH, Perry-Woodford ZL, Tekkis PP, Ciclitira PJ, Nicholls RJ.  Extended spectrum beta-lactamase-producing bacteria and Clostridium difficile in patients with pouchitis.  Alimentary Pharmacology & Therapeutics 2010;32:664-9.

McLaughlin SD, Clark SK, Tekkis PP, Nicholls RJ, Ciclitira PJ.  The bacterial pathogenesis and treatment of pouchitis.  Therapeutic Advances in Gastroenterology 2010;3:335-48.

McLaughlin SD, Perry-Woodford ZL, Clark SK, Johnson MW, Tekkis PP, Ciclitira PJ, Nicholls RJ.  Osteoporosis in patients over 50 years of age following restorative proctocolectomy for ulcerative colitis: is DXA screening warranted?  Inflammatory Bowel Diseases 2010;16:250-5.

McLaughlin SD, Walker AW, Churcher C, Clark SK, Tekkis PP, Johnson MW, Parkhill J, Ciclitira PJ, Dougan G, Nicholls RJ, Petrovska L.  The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing.  Annals of Surgery 2010;252:90-8.

McLaughlin SD, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ.  An open study of maintenance antibiotic therapy for chronic antibiotic-dependent pouchitis: efficacy, complications and outcome.  Colorectal Disease 2011;13:438-44.