Grants Funded in 2010
Principal Investigator: Arasaradnam, Ramesh P., MB BCh, Ph.D.
Proposal No. IBD-0309
Applicant Organization: University Hospital Coventry & Warwick, University of Warwick (England)
Project Title: Real-time identification and monitoring of inflammatory bowel disease through the bio-odorant signature of colonic fermentation (fermentonomics)
Period of Award: December 1, 2010 - November 30, 2011
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Principal Investigator: Clerici, Mario S., M.D.
Proposal No. IBD-0294
Applicant Organization: Università degli Studi di Milano (Italy)
Project Title: Role of pathogen-driven selection in shaping the predisposition to inflammatory bowel disease: identification of disease susceptibility alleles
Period of Award: September 1, 2010 - May 31, 2012
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Principal Investigator: Etminan, Mahyar, PharmD, MSc
Proposal No. IBD-0291
Applicant Organization: University of British Columbia (Canada)
Project Title: Isotretinoin and risk of inflammatory bowel disease: a retrospective cohort study
Period of Award: February 1, 2010 - June 30, 2011
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Principal Investigator: Fedorak, Richard Neil, M.D.
Proposal No. IBD-0264R
Applicant Organization: University of Alberta (Canada)
Project Title: The IBD metabolome project: human metabolomic analysis of patients with IBD
Period of Award: January 1, 2010 - December 31, 2011
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Principal Investigator: Hartmann, Susanne, Ph.D.
Proposal No. IBD-0290
Applicant Organization: Humboldt University Berlin (Germany)
Project Title: Treatment of inflammatory bowel disease with helminth immunomodulators
Period of Award: March 1, 2010 - February 28, 2011
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Principal Investigator: Kamm, Michael A., MBBS, M.D.
Proposal No. IBD-0298R
Applicant Organization: Australasian Gastro Intestinal Research Foundation, Ltd. (Australia)
Project Title: The gut microbiota in the East and West -- in the healthy population, inflammatory bowel disease patients, and relatives. The ENIGMA (eastern inflammatory bowel disease gut microbiota) study
Period of Award: July 1, 2010 - June 30, 2012
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Principal Investigator: Krissansen, Geoffrey W., Ph.D.
Proposal No. IBD-0274R
Applicant Organization: University of Auckland (New Zealand)
Project Title: Circulating microRNAs in Crohn's disease: can they provide insights into disease pathogenesis and might they have diagnostic utility?
Period of Award: February 1, 2010 - October 31, 2011
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Principal Investigator: Mizoguchi, Emiko, M.D., Ph.D.
Proposal No. IBD-0304
Applicant Organization: Massachusetts General Hospital (U.S.A.)
Project Title: Chitinase 3-like proteins in colitis-associated carcinogenesis
Period of Award: September 1, 2010 - August 31, 2012
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Principal Investigator: Monteleone, Giovanni, M.D., Ph.D.
Proposal No. IBD-0301R
Applicant Organization: University Tor Vergata of Rome (Italy)
Project Title: Effect of Smad7 antisense oligonucleotide on clinical, laboratory and immunological variables in patients with active Crohn's disease: the first human experience
Period of Award: July 1, 2010 - June 30, 2012
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Principal Investigator: Mudter, Jonas, M.D.
Proposal No. IBD-0200R2
Applicant Organization: University of Erlangen (Germany)
Project Title: The role of IRF transcription factors in DC and T cell differentiation in inflammatory bowel disease
Period of Award: January 1, 2010 - June 30, 2011
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Principal Investigator: Parekkadan, Biju, Ph.D.
Proposal No. IBD-0276R
Applicant Organization: Massachusetts General Hospital (U.S.A.)
Project Title: Antigen-specific mesenchymal stem cell grafts for inflammatory bowel disease
Period of Award: January 1, 2010 - December 31, 2012
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Principal Investigator: Silver, Andrew R., Ph.D.
Proposal No. IBD-0289R
Applicant Organization: Queen Mary and Westfield College, University of London (England)
Project Title: MicroRNA expression profiles in blood and tissues in patients with chronic ulcerative colitis: identifying biomarkers for progression to cancer
Period of Award: February 1, 2010 - June 30, 2012
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Principal Investigator: Smid, Scott, Ph.D.
Proposal No. IBD-0268R
Applicant Organization: The University of Adelaide (Australia)
Project Title: Functional role of the endogenous cannabinoid system in inflammatory bowel disease
Period of Award: February 1, 2010 - February 28, 2011
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Principal Investigator: Sparrow, Miles Patrick, MBBS
Proposal No. IBD-0245
Applicant Organization: Alfred Health (Australia)
Project Title: Use of adjunctive allopurinol in azathioprine/6-mercaptopurine non-responders to optimize 6-thioguanine nucleotide production and improve clinical outcomes
Period of Award: April 1, 2010 - March 31, 2011
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Principal Investigator: Walters, Julian, MA, MB
Proposal No. IBD-0300
Applicant Organization: Imperial College London (England)
Project Title: Diarrhea in Crohn's: investigating the role of the novel ileal hormone fibroblast growth factor 19 (FGF19) in disease assessment and pathogenesis of diarrhea
Period of Award: October 1, 2010 - September 30, 2012
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Principal Investigator: Ziring, David, M.D.
Proposal No. IBD-0285
Applicant Organization: University of California, Los Angeles (U.S.A.)
Project Title: Vitamin D supplementation as non-toxic immunomodulation in children with Crohn's disease
Period of Award: January 1, 2010 - December 31, 2011
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