 |
Fourth Annual
BMRP Investigator Meeting |
March 23-24, 2006
Los Angeles, California
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INVITED
SPEAKERS:
 Shanahan,
Fergus, M.D.
Professor and Chairman, Department of Medicine; Director, Alimentary
Pharmabiotic Centre, Biosciences Institute, University College Cork
(United Kingdom)
"Promises, promises - a perspective on IBD research directions"
Scolnick, Edward, M.D.
Director, Psychiatry Initiative, Broad Institute at MIT & Harvard; former
President, Merck Research Laboratories
"The route to drug discovery: a few examples"
Presentation
SCIENTIFIC
SUMMARY OF MEETING:
 Shanahan,
Fergus, M.D.
Professor and Chairman, Department of Medicine; Director, Alimentary
Pharmabiotic Centre, Biosciences Institute
University College Cork
(United Kingdom)
PRESENTATIONS BY
BMRP INVESTIGATORS:
(partial list of talks and posters)
 Baumgart,
Daniel C., M.D.
Medical School of the Humboldt - University of Berlin
(Germany)
"Role of native human dendritic cells in inflammatory bowel disease"
 Behr,
Marcel A., M.D.
McGill University
(Montreal, Quebec, Canada)
"Detection of Mycobacterium avium paratuberculosis in Crohn's
tissue"
Abstract
 Bienenstock,
John, M.D.
McMaster University
(Hamilton, Ontario, Canada)
"The vagus nerve is involved in regulation of intestinal
inflammation"
 Body-Malapel,
Mathilde, Ph.D.
University of Michigan
(Ann Arbor, U.S.A.)
"Role of Nod2 in the control of Paneth cell function and intestinal
microflora"
Abstract
 Braun,
Jonathan, M.D., Ph.D.
University of California, Los Angeles
(U.S.A.)
"Intestinal microbiota and systemic immune homeostasis"
Abstract
 Büchner,
Kerstin, M.D.
Charitè-Universitätsmedizin Berlin, Campus Benjamin Franklin
(Germany)
"CD4+CD25+ T regulatory cells in inflammatory bowel disease"
Abstract
 Clancy,
Robert, M.D., Ph.D.
University of Newcastle
(Australia)
"Mycobacterium avium ss paratuberculosis promotes but
does not cause Crohn's disease"
Abstract
 Danese, Silvio, M.D.
Catholic University of Rome
(Italy)
"Angiogenesis as a novel component in the pathogenesis of
inflammatory bowel disease"
Abstract
 Denson, Lee A., M.D.
Cincinnati Children's Hospital Medical Center (Ohio, U.S.A.)
"STAT5b promotes mucosal tolerance in Crohn's disease and murine
colitis"
Presentation
 Ebert,
Ellen C., M.D.
University of Medicine and Dentistry of New Jersey-Robert Wood
Johnson Medical School
(New Brunswick, U.S.A.)
"Sera from active ulcerative colitis contain IgG antibodies against
human tropomyosin isoform 5(hTM5) that kills colonic epithelial
cells through antibody and complement lysis"
 Föll,
Dirk, M.D.
University of Münster
(Germany)
"Neutrophil-derived S100A12 (EN-RAGE): Molecular basis of its
expression, secretion, receptor-binding, and its role in inflammatory
bowel disease"
Abstract
 Gewirtz,
Andrew, Ph.D.
Emory University
(Atlanta, Georgia, U.S.A.)
"Humoral immune response to flagellin requires T-cells and activation
of innate immunity"
Presentation
 Greeley,
George H., Jr., Ph.D.
University of Texas at Galveston
(U.S.A.)
"Involvement of the apelin in colonic epithelial proliferation"
Abstract
 Hoff, Sebastian
Technical University of Munich
(Germany)
"Enteric glia in intestinal inflammation"
Abstract
Poster
 Kirkwood,
Carl D., Ph.D.
Murdoch Childrens Research Institute
(Parkville, Australia)
"Does a viral agent induce Crohn’s disease? A search for
viral agents in children with early onset Crohn’s disease"
Abstract
 Koide,
Yukio, M.D., Ph.D.
Hamamatsu University School of Medicine
(Japan)
"Curcumin maintenance therapy for ulcerative colitis:
multicenter, double-blind, placebo-controlled, randomized clinical
trial"
Abstract
 Lamps,
Laura W., M.D.
University of Arkansas for Medical Sciences
(Little Rock, U.S.A.)
"Pathogenic Yersinia DNA detection in Crohn's disease"
Abstract
 Leiter,
Edward H., Ph.D.
The Jackson Laboratory
(Bar Harbor, Maine, U.S.A.)
"Subcongenic analysis of Cdcs1, a major colitis susceptibility
modifier in mice"
Abstract
Levitt, Michael, M.D.
Minnesota Veterans Research Institute
(Minneapolis, U.S.A.)
"Possible role of hydrogen sulfide in the pathogenesis of pouchitis
and ulcerative colitis"
Presentation
 Li,
Xuhang, Ph.D.
Johns Hopkins University
(Baltimore, Maryland, U.S.A.)
"Proteomic study of inflammatory bowel disease"
Abstract
 Maggio-Price,
Lillian, V.M.D., Ph.D.
University of Washington
(Seattle, U.S.A.)
"Absence of T and B cells in Smad3-KO mice with TGF-b
dysregulation increases susceptibility to bacterial-induced
inflammation and colon cancer"
Abstract
 Mizoguchi, Atsushi, M.D., Ph.D.
Massachusetts General Hospital
(Boston, U.S.A.)
"Therapeutic approach using interleukin-22 in experimental colitis"
Abstract
 Morrison,
Douglas, Ph.D.
University of Glasgow
(Scotland)
"Novel strategies for the colonic
provision of butyric acid"
Abstract
 Muench,
Marcus, Ph.D.
Blood Systems Research Institute
(San Francisco, California, U.S.A.)
"Maternal microchimerism in inflammatory bowel disease"
Abstract
 Papadakis,
Konstantinos A., M.D.
Cedars-Sinai Medical Center
(Los Angeles, California, U.S.A.)
"Phenotypic and functional characterization of CCR9+ T lymphocytes in small intestinal Crohn's disease"
Abstract
 Pender,
Sylvia L. F., Ph.D.
University of Southampton
(United Kingdom)
"Role of macrophage metalloelastase (MMP-12) in inflammatory bowel
disease"
 Plevy,
Scott E., M.D.
University of Pittsburgh
(Pennsylvania, U.S.A.)
"Clostridium perfringens as a novel therapeutic
vehicle in inflammatory bowel disease"
Abstract
Presentation
 Rampton,
David S., BM, DPhil
Queen Mary, University of London
(United Kingdom)
"The effect of acute psychological stress on systemic and rectal mucosal
measures of inflammation in ulcerative colitis"
"The effect of hypnotherapy on systemic and rectal mucosal measures of
inflammation in ulcerative colitis"
Abstract #1
Abstract #2
 Rosenberger,
Carrie, Ph.D.
Institute for Systems Biology
(Seattle, Washington, U.S.A.)
"Role of CREB transcription factors in regulating inflammatory
responses"
Abstract
 Sartor,
R. Balfour, M.D.
University of North Carolina at Chapel Hill
(U.S.A.)
"Cleavage products of kininogen variably induce pro-inflammatory
cytokines by Fisher rat splenocytes"
Abstract
 Srivastava,
Anand, Ph.D.
University of California, San Diego
(La Jolla, U.S.A.)
"Embryonic
stem cells improve colitis and decrease IL-12 levels in the colitis
mice"
Abstract
 Török,
Helga-Paula, M.D.
Ludwig-Maximilians University
(Munich, Germany)
"NOD2/CARD15 mutations and apoptosis in Crohn's disease"
Abstract
 Vandenbroucke,
Klaas, Ph.D.
Flanders Interuniversity Institute for Biotechnology
(Zwijnaarde, Belgium)
"Treatment of murine colitis by Lactococcus lactis secreting
anti-tumor necrosis factor Nanobodies™"
Abstract
 van
der Zee, Ruurd, Ph.D.
Utrecht University
(The Netherlands)
"Heat shock proteins as therapeutic agents for inflammatory bowel
disease"
Abstract
 Visser,
Lydia, Ph.D.
University of Groningen
(The Netherlands)
"Ex vivo treatment of biopsies in inflammatory bowel disease
with galectin-1"
 Zasloff, Michael, M.D., Ph.D.
Georgetown University
(Washington, D.C., U.S.A.)
"Rejection in the setting of small intestinal transplantation in man:
a failure of intestinal innate immunity"
Presentation
|
The
Broads are dedicated to advancing medical knowledge by funding innovative
IBD research.
Dr.
Hollander is the BMRP Director and a Professor of Medicine at UCLA.