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Fifth Annual BMRP Investigator Meeting

February 8-9, 2007
Los Angeles, California

(NOTE:  You must have Adobe Acrobat software in order to open the presentation documents.  Click here to download this free software.)


INVITED SPEAKER:

Mayer, Lloyd, M.D.
Professor and Director, Center for Immunobiology; Professor, Divisions of Clinical Immunology and Gastroenterology; Professor, Department of Microbiology; Mount Sinai School of Medicine
(New York, New York, U.S.A.)

"Revisiting paradigms in IBD pathogenesis"

Presentation

"Scientific Summary of Meeting"

Presentation


PRESENTATIONS BY BMRP INVESTIGATORS
(partial list of talks and posters)

 

Razvan, Arsenescu, M.D.
University of Kentucky
(Lexington, U.S.A.)

"Adiponectin in Crohn's disease.  Phenotype-genotype correlations and implications in management"


 


 

Bienenstock, John, M.D.
 McMaster University
 (Hamilton, Ontario, Canada)
 
 "While the alpha7 nicotinic receptor pathway is involved in constitutive downregulation

of acute and chronic intestinal inflammation,
it is not used by probiotics"
 

 


 

Büning, Carsten, M.D.
Charité-Universitätsmedizin Berlin, Campus Mitte
(Germany)


"Genes involved in epithelial integrity as
risk factors for IBD"

Abstract

 



Chiorean, Michael V., M.D.

Indiana University

(Indianapolis, U.S.A.)

"Correlation of CT enteroclysis and surgical pathology in patients with Crohn's disease"

Poster


 


Craig, Robert M., M.D.
Northwestern University
(Chicago, Illinois, U.S.A.)

"Autologous hematopoietic stem cell transplantation (HSCT) for severe Crohn's disease (CD), 4 year follow-up"

Abstract


Danese, Silvio, M.D.
Istituto Clinico Humanitas
(Milan, Italy)

"Angiogenesis blockade as a new therapeutic approach to experimental colitis
"

Presentation
 



Föll, Dirk, M.D.
University of Münster
(Germany)

"Fecal S100A12:  A non-invasive stool marker released from inflamed mucosa during active inflammatory bowel disease"

Abstract

 


 

Fortun, Paul J., B.Med.Sc.
University of Nottingham 
(United Kingdom)

"Hookworms as therapy in Crohn's disease"

Abstract



 



Garrity-Park, Megan
Mayo Clinic
(Rochester, Minnesota, U.S.A.)

"Clinical, pathological and genotypic variations in UC-CRC: preliminary findings"

Abstract


 


Hale, Laura P., M.D., Ph.D.
Duke University 
(Durham, North Carolina, U.S.A.)

"Therapy of inflammatory bowel disease using LMP-420"

Abstract

 


 

Hawkey, Chris J., M.D.
University of Nottingham

(United Kingdom)

"Autologous hematopoietic stem cell transplantation in Crohn's disease: the
ASTIC trial"

Presentation

 



Hugot, Jean-Pierre, M.D., Ph.D.
INSERM, Hopital Robert Debr
é
(Paris, France)

"CARD15/NOD2 modulates Peyer's patch phenotype in mice"

Abstract

 



Kapp, Kerstin, Ph.D.

Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin
(Germany)

"CD4+CD25+ T regulatory cells in IBD"

Abstract

 

 



Kirkwood, Carl D., Ph.D.
Murdoch Childrens Research Institute

(Parkville,  Australia)

"Does a viral agent induce Crohn's disease?  A search for infectious agents in children
with early onset Crohn's disease"

 

 



Kokkotou, Efi, M.D., Ph.D.
Beth Israel Deaconess Medical Center
(Boston, Massachusetts, U.S.A.)

"Targeting melanin-concentrating hormone (MCH) as a novel treatment for inflammatory bowel disease"


 



Mizoguchi, Atsushi, M.D., Ph.D.

Massachusetts General Hospital 
(Boston, U.S.A.)

"Therapeutic approach using interleukin-22 in experimental colitis"

Abstract



 


Ortner, Maria-Anna, M.D.
Centre Hospitalier Universitare Vaudois
(Lausanne, Switzerland)

"Photodynamic therapy as a novel therapeutic approach for the treatment of Crohn's disease"

Abstract



Pender, Sylvia L. F., Ph.D.
University of Southampton
(United Kingdom)

"Role of macrophage metalloelastase (MMP-12) in inflammatory bowel disease"



 


 

Ramakrishna, Balakrishnan, M.D., Ph.D.
Christian Medical College 
(Vellore, Indian)

"Exploring the relationship between Crohn's disease and hookworm infestation in a hitherto low prevalence area for Crohn's disease"

Abstract

 



Spiller, Robin C., M.D.
University of Nottingham
(United Kingdom)

"Altered enteric nerve phenotype and visceral sensation in ulcerative colitis"

Abstract

 



Suskind, David L, M.D.
University of Washington
(Seattle, U.S.A.)

"Maternal microchimerism in inflammatory bowel disease"




 



van Eden, Willem, Ph.D.
Utrecht University
(The Netherlands)

"Heat shock proteins can have disease suppressive therapeutic effects in inflammatory bowel disease models"

Abstract
 



Visser, Lydia, Ph.D.
University of Groningen
(The Netherlands)
 
 "Ex vivo treatment of biopsies in inflammatory bowel disease with galectin-1
"
 
 


 


 

Xiong, Huabao, M.D.
Mount Sinai School of Medicine
(New York, New York, U.S.A.)

"Blocking TLR signaling pathway by TLR peptides in the treatment of colitis"



 



Zasloff, Michael, M.D., Ph.D.
Georgetown University
(Washington, D.C., U.S.A.)

"Insights in to the function of the NOD2 gene in intestinal immunity from studies of human small bowel transplantation"

Abstract


 

 

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Goals

The BMRP funds innovative clinical or basic IBD research projects that are in the early stages of exploration and will benefit IBD patients.


Eli & Edythe L. Broad

The Broads are dedicated to advancing medical knowledge by funding innovative IBD research.


Daniel Hollander, M.D.

Dr. Hollander is the BMRP Director and a Professor of Medicine at UCLA.


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