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Grants Funded in 2007

 


Principal Investigator:  Bossuyt, Xavier, M.D., Ph.D.

Proposal No. IBD-0202

Applicant Organization:  Katholieke Universiteit Leuven (Belgium)

Project Title:  Identification of target antigens of antibodies in inflammatory bowel disease

Period of Award:  May 1, 2007 – April 30, 2008

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Principal Investigator:  Cao, Caroline, Ph.D.

Proposal No. IBD-0196R

Applicant Organization:  Tufts University (U.S.A.)

Project Title:  Image-guided research in colonoscopy to improve diagnosis of inflammatory bowel disease

Period of Award:  February 1, 2007 – January 31, 2009

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Principal Investigator:  Croese, John, MBBS, M.D.

Proposal No. IBD-0214R

Applicant Organization:  Queensland Institute of Medical Research (Australia)

Project Title:  Inoculating celiac disease patients with the human hookworm Necator americanus: evaluating immunity and gluten sensitivity

Period of Award:  December 1, 2007 – November 30, 2008

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Principal Investigator:  Daunert, Sylvia, Pharm.D., Ph.D.

Proposal No. IBD-0198R

Applicant Organization:  University of Kentucky Research Foundation (U.S.A.)

Project Title:  Non-invasive biosensors for the diagnosis and management of Crohn's disease

Period of Award:  June 1, 2007 – May 31, 2008

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Principal Investigator:  Denson, Lee A., M.D.

Proposal No. IBD-0211

Applicant Institution:  Cincinnati Children's Hospital Medical Center (U.S.A.)

Project Title:  GM-CSF bioactivity and IBD phenotype

Award Period:  October 1, 2007 - September 30, 2008

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Principal Investigator:  Fayad, Raja, M.D.

Proposal No. IBD-0199R

Applicant Institution:  The Board of Trustees of the University of Illinois (U.S.A.)

Project Title:  Adipose tissue macrophages: role in the development of strictures in Crohn's disease

Award Period:  October 1, 2007 - September 30, 2008

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Principal Investigator:  Föll, Dirk, M.D.

Proposal No. IBD-0201R

Applicant Institution:  University Hospital of Münster (Germany)

Project Title:  Functional characterization of GM-CSF induced monocyte subsets and analysis of their relevance in Crohn's disease

Award Period:  September 1, 2007 - August 31, 2008

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Principal Investigator:  Guillemin, Karen J., Ph.D.

Proposal No. IBD-0209

Applicant Institution:  University of Oregon (U.S.A.)

Project Title:  Do changes in gut motility promote gut inflammation by altering the composition of gut microbiota?

Award Period:  August 1, 2007 - July 31, 2008

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Principal Investigator:  Hurlstone, David Paul, MB ChB, M.D.

Proposal No. IBD-0219

Applicant Institution:  Sheffield Teaching Hospitals NHS Foundation Trust (United Kingdom)

Project Title:  A randomized Phase II clinical trial to investigate the diagnostic utility of confocal chronoscopic endomicroscopy for the detection and characterization of intraepithelial neoplasia in chronic ulcerative colitis

Award Period:  October 8, 2007 - October 7, 2008

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Principal Investigator:  Jensen, Liselotte, Ph.D.

Proposal No. IBD-0192R

Applicant Organization:  University of Pennsylvania (U.S.A.)

Project Title:  Interleukin-1 system in inflammatory bowel disease and implications for the development of novel therapies

Period of Award:  March 1, 2007 – February 29, 2009

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Principal Investigator:  Kaplan, Gilaad G., M.D., M.P.H.

Proposal No. IBD-0216R

Applicant Organization:  University of Calgary (Canada)

Project Title:  The effect of air pollution on the development of Crohn's disease and ulcerative colitis in England and Wales

Period of Award:  September 1, 2007 – August 31, 2008

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Principal Investigator:  Kwon, John H., M.D., Ph.D.

Proposal No. IBD-0212

Applicant Organization:  Johns Hopkins University (U.S.A.)

Project Title:  The differential expression of microRNA in ulcerative colitis patients and their regulation of MIP-2α expression

Period of Award:  July 1, 2007 – June 30, 2008

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Principal Investigator:  Ma, Xiaojing, Ph.D.

Proposal No. IBD-0210R2

Applicant Institution:  Weill Medical College of Cornell University (U.S.A.)

Project Title:  The Crohn’s disease-associated NOD23020insC mutant has an acquired activity as an inhibitor of IL-10 production

Award Period:  October 1, 2007 - September 30, 2008

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Principal Investigator:  Montgomery, Scott M., Ph.D.

Proposal No. IBD-0204R2

Applicant Organization:  Karolinska Institutet (Sweden)

Project Title:  Markers of perinatal bowel colonization and pediatric Crohn's disease risk

Period of Award:  September 1, 2007 – August 31, 2008

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Principal Investigator:  Powrie, Fiona M., DPhil

Proposal No. IBD-0203

Applicant Organization:  University of Oxford (United Kingdom)

Project Title:  Role of TGF-β in the pathogenesis of IBD

Period of Award:  August 1, 2007 – July 31, 2008

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Principal Investigator:  Rampton, David S., DPhil

Proposal No. IBD-0213R

Applicant Organization:  Queen Mary and Westfield College, University of London (United Kingdom)

Project Title:  Hypnotherapy for prevention of relapse in ulcerative colitis: a randomized, single-blinded, controlled clinical trial

Period of Award:  October 1, 2007 – September 30, 2008

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Principal Investigator:  Ramratnam, Bharat, M.D.

Proposal No. IBD-0194R

Applicant Organization:  Rhode Island Hospital (U.S.A.)

Project Title:  Transient gene therapy for inflammatory bowel disease

Period of Award:  March 15, 2007 – March 14, 2008

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Principal Investigator:  Sanderson, Jeremy D., M.D.

Proposal No. IBD-0215R

Applicant Organization:  King's College London (United Kingdom)

Project Title:  The persistence of bacteria in lamina propria macrophages in Crohn's disease: role in pathogenesis

Period of Award:  November 1, 2007 – October 31, 2008

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Principal Investigator:  Savidge, Tor C., Ph.D.

Proposal No. IBD-0188R

Applicant Organization:  University of Texas Medical Branch at Galveston (U.S.A.)

Project Title:  To examine the therapeutic potential of a novel mucosal barrier-inducing factor in the treatment of Crohn's disease

Period of Award:  March 1, 2007 – February 29, 2008

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View Grant Publications

 


Principal Investigator:  Shen, Bo, M.D., M.S.

Proposal No. IBD-0218

Applicant Organization:  The Cleveland Clinic Foundation (U.S.A.)

Project Title:  Pouchitis:  a human model for bacteria-host interaction in inflammatory bowel disease

Period of Award:  November 1, 2007 – October 31, 2008

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Principal Investigator:  Sturm, Andreas, M.D.

Proposal No. IBD-0186R

Applicant Organization:  Charité - Universitätsmedizin Berlin (Germany)

Project Title:  Galectin-2:  Evaluation of a novel anti-inflammatory approach in the treatment of inflammatory bowel disease

Period of Award:  January 1, 2007 – December 31, 2008

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Principal Investigator:  Segal, Anthony W., M.D., Ph.D., D.Sc.

Proposal No. IBD-0193R

Applicant Organization:  University College London (United Kingdom)

Project Title:  Impaired innate immunity and the pathogenesis of Crohn's disease

Period of Award:  March 1, 2007 – February 29, 2008

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View Lay Summary

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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As of 04/08/2008


Letter of Interest

The first step in applying is to submit a Letter of Interest (LOI). Investigators whose LOIs fit the BMRP's criteria and interest areas will be invited to submit a full grant application.


Review Process

A committee does not review or make decisions on proposals. Leading investigators in each research area provide individual reviews and suggestions to improve the proposals.


Funded Grants

Review the list of funded grants before you submit a LOI. Included are scientific abstracts, lay summaries, presentations made at BMRP Investigator meetings, publications resulting from BMRP funding and final technical progress reports.


BMRP Statistics

See data on Principal Investigators, amounts awarded, etc.

 


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